PFAS Testing Leadership

York Analytical is the preeminent laboratory in the Northeast for expert PFAS testing and analysis, with licensing in six states. With senior technical leadership, expanded laboratory capacity and instrumentation, the York team will stay on top of evolving PFAS regulations to deliver the fastest TATs in the region.

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Your PFAS Team is Local

Our state-of-art PFAS laboratories are located in the heart of our service region, in Queens, NY and Toms River, NJ. We mobilize our regional field service teams to meet clients’ needs from Albany to Philadelphia, covering Connecticut, New York and New Jersey. Your samples are never re-packaged and shipped to an outside lab, they get on our instruments in a timely manner to ensure best turnaround times.

Your PFAS Laboratory is State-of-the-Art

York has invested aggressively and worked continuously with vendors to pioneer new technologies to become the most efficient PFAS laboratory network in the region. With a fleet of Aglient’s latest HPLC-MS/MS systems, and automated PromoChrom SPE extraction equipment, laboratory capacity is high and we provide results in as little as three business days.

Your PFAS Team is Innovative

Expertise that is second to none. York’s senior technical team developed the methods for preparation and analysis using isotope dilution with HPLC/MS-MS while developing and implementing methods for drinking water using EPA methods 537, 537.1 and 533 as well as non-drinking water methods 537m (isotope dilution) and EPA 1633.

PFAS Methods

We are certified to analyze drinking water samples by EPA 537 and EPA 537.1 and 533 in New York, Connecticut and New Jersey, Pennsylvania, Massachusetts and New Hampshire. We also analyze groundwater and soil by EPA 537m (a modified isotope dilution method), along with EPA 1633 which New York requires for all regulated projects. Please refer to the table below for the PFAS compounds we’re able to analyze and their associated methods.

Please refer to the table below for the PFAS compounds we’re able to analyze and their associated methods. Should you have any questions, our

PFAS Compounds By Method

Compound EPA 537M* EPA 537.1 EPA 533 EPA 1633 EPA 537
Perfuoro-n-butanoic acid (PFBA)
Perfuoro-n-pentanoic acid (PFPeA)
Perfuorohexanoic acid (PFHxA)
Perfuoroheptanoic acid (PFHpA)
Perfuorooctanoic acid (PFOA)
Perfuorononanoic acid (PFNA)
Perfuorodecanoic acid (PFDA)
Perfuoroundecanoic acid (PFUnA)
Perfuorododecanoic acid (PFDoA)
Perfuorotridecanoic acid (PFTrDA)
Perfuorotetradecanoic acid (PFTeDA)
Perfuorobutanesulfonic acid (PFBS)
Perfuoro-1-pentanesulfonate (L-PFPeS)
Perfuorohexanesulfonic acid (PFHxS)
Perfuoro-1-heptanesulfonate (L-PFHpS)
Perfuorooctanesulfonic acid (PFOS)
Perfuorononanesulfonate (L-PFNS)
Perfuoro-1-decanesulfonate (L-PFDS)
Perfuorododecanesulfonic acid (PFDoS)
1H.1H.2H.2H-perfuoro-1-decanesulfonate (8:2 FTS)
1H.1H.2H.2H-perfuoro-1-hexanesulfonate (4:2 FTS)
1H.1H.2H.2H-perfuoro-1-octanesulfonate (6:2 FTS)
Perfuoro-1-octanesulfonamide (FOSA)
N-ethylperfuorooctanesulfonamedoacetic acid (N-EtFOSAA)
N-methylperfuorooctanesulfonamdeoacetic acid (N-MeFOSAA)
N-methylperfuorooctanesulfonamide (N-MeFOSA)
N-ethylperfuorooctanesulfonamide (N-EtFOSA)
N-methylperfuorooctanesulfonamidoethanol (N-MeFOSE)
N-ethylperfuorooctanesulfonamidoethanol (N-EtFOSE)
Hexafuoropropylene oxide-dimer acid (GenX/HFPO-DA)
Dodecafuoro-3H-4.8-dioxanonanoate (ADONA)
Nonafuoro-3.6-dioxaheptanoic acid (NFDHA)
9-Chlorohexadecafuoro-3-oxanone-1-sulfonic acid (9CL-PF3ONS)
11-chloroeicosafuoro-3-oxaundecane-1-sulfonic acid (11CL-PF3OUdS)
Perfuoro-2-ethoxyethanesulfonic acid (PFEESA)
Perfuoro-4-methoxybutanoic acid (PFMBA)
Perfuoro-3-methoxypropanoic acid (PFMPA)
3-perfuoropropylpropanoic acid (3:3 FTCA)
2H.2H.3H.3H-perfuorooctanoic acid (5:3 FTCA)
3-perfuoroheptylpropanoic acid (7:3 FTCA)

How We Do It

PFAS analysis can be broken down into three basic steps: extraction, concentration, and instrumental analysis. Once we’ve acquired our data, we can upload it to our Laboratory Information Management System (LIMS) for final reporting to you.

However, like an efficient analytical process, the devil is in the details, and having good sampling procedures at the outset will go a long way to obtaining the best data possible for your project.

PFAS Sampling: Why it’s Important to You

PFAS compounds are ubiquitous in the environment. They’re present in the clothing we wear, the fabric softener we use, on the inside of food wrappers, and even in some lotions. Special considerations should be taken prior to any sampling event.

Please see our sampling guides for detailed instructions to follow when collecting samples. We are analyzing your samples down to part per trillion levels so cross-contamination prevention is an important consideration.

PFAS Sampling Guides


A Solid Phase Extraction (SPE) technique is used to extract target PFAS compounds from water and soil samples.  PFAS compounds are absorbed onto a specialized media and then eluted into a liquid extract.  Utilizing the latest instrumentation from Promochrom Technologies, York has been able to dramatically increase its efficiency by being able to simultaneously extract samples, rather than sequentially.


Sample extracts are then concentrated under a stream of Ultra High Purity Nitrogen to a volume appropriate to the sample matrix.  Adding this step ensures that our clients receive results to a detection limit often surpassing state and federal regulations.  


York’s fleet of Agilent’s top-of-the-line High Pressure Liquid Chromatography Tandem Mass Spectrometer (HPLC-MS/MS) systems analyze PFAS samples. The HPLC system is used to separate compounds of concern into individual components so as they enter the detector (the MS/MS) we’re able to measure the concentration of each compound individually down to very low levels.

In the MS/MS, a targeted mass spectrometry (MS) technique called multiple reaction monitoring (MRM) is employed to allow measurement of specific compounds in a complex matrix like groundwater or soil samples.  Each compound has a unique transition, or “signature,” within the MS allowing for accurate qualitative identification.  This technology also lends itself to an isotope dilution application.

Why Isotope Dilution?

An isotope dilution approach to PFAS testing is utilized because it’s the most accurate way to measure compounds of concern, especially down to very low levels.  At the beginning of every sample preparation, known quantities of an isotopic analogue of each PFAS compound is added to a sample.  While these compounds are the same in every way as their native counterpart, replacing some atoms carbon-13 or deuterium means that they will respond differently on the instrument and then can be measured independently.

The isotopically labeled compound will behave in the exact same manner as any native compound present in a sample.  Therefore, a direct measurement of extraction efficiency for each individual analyte allows for a correction factor to be applied to each result, providing the most accurate and reliable data.